Abundance, fatty acid composition and saturation index of neutral lipids in colorectal cancer cell lines

Lipid droplets, the dynamic organelles that store triglycerides (TG) and cholesterol esters (CE), are highly accumulated in colon cancer cells. This work studies TG CE subspecies profile carcinoma cell lines, SW480 derived from primary tumor, SW620 a metastasis of same tumor. It was previously reported total content is dramatically higher cells; however, has not been investigated detail. The presented here confirms significantly Moreover, fatty acid (FA) composition altered cells, with significant decrease abundance saturated triglycerides. resulted decreased saturation index also